Researchers from the University of Colorado Anschutz Medical Campus believe they have identified the central mechanism behind cognitive decline associated with normal aging:
“The mechanism involves the misregulation of a brain protein known as CaMKII which is crucial for memory and learning,” said the study’s co-senior author Ulli Bayer, Ph.D., professor of pharmacology at the University of Colorado School of Medicine.
[…]
Bayer said that aging in mice and humans both decrease a process known as S-nitrosylation, the modification of specific brain proteins including CaMKII.
“The current study now shows a decrease in this modification of CaMKII is sufficient to cause impairments in synaptic plasticity and in memory that are similar in aging,” Bayer said.
Normal aging reduces the amount of nitric oxide in the body. That in turn reduces nitrosylation which reduces memory and learning ability, the study said.
https://longevity.technology/lifestyle/top-10-foods-to-boost-your-nitric-oxide-levels/
ED medication works by boosting nitric oxide levels. Seems like a clear opportunity for researchers to test the effect of boosting NO on cognitive decline with a longitudinal study.
Getting funding from a college or government board (but I repeat myself) for research into modalities that relate to improvements in male fertility or T levels or manliness in general is all but impossible. Just by coincidence of course.
Pseudo-Chrysostom: “Getting funding from a college or government board (but I repeat myself) for research into modalities that relate to improvements in male fertility or T levels or manliness in general is all but impossible. Just by coincidence of course.”
You know as well as everyone that managing healthy, vital men is an exceptionally troublesome endeavor, the very most. Nor will any establishment institution ever emit an effective stratagem of debt elimination or lawyer humiliation or wagie emancipation. Such is life.
https://youtube.com/watch?v=h2a20YL5mvg