The origin of The Selfish Gene is intriguing. Dawkins revealed in the first volume of his memoirs, An Appetite for Wonder (Bantam, 2013; see E. Scott Nature 501, 163; 2013), that the idea of selfish genes was born ten years before the book was published. In 1966, the Dutch biologist Niko Tinbergen asked Dawkins, then a research assistant with a new doctorate in animal behaviour, to give some lectures in his stead. Inspired by Hamilton, Dawkins wrote in his notes (reproduced in An Appetite for Wonder): “Genes are in a sense immortal. They pass through the generations, reshuffling themselves each time they pass from parent to offspring … Natural selection will favour those genes which build themselves a body which is most likely to succeed in handing down safely to the next generation a large number of replicas of those genes … our basic expectation on the basis of the orthodox, neo-Darwinian theory of evolution is that Genes will be ‘selfish’.”
Dawkins began writing the book in 1973, and resumed it in 1975 while on sabbatical. At the suggestion of Desmond Morris, the zoologist and author of The Naked Ape (Jonathan Cape, 1967), Dawkins showed some draft chapters to Tom Maschler of Jonathan Cape, who strongly urged that the title be changed to ‘The Immortal Gene’. Today, Dawkins regrets not taking the advice. It might have short-circuited the endless arguments, so beloved of his critics and so redolent of the intentional stance (in which we tend to impute mental abilities to unconscious things, from thunderstorms to plants), about whether selfishness need be conscious. It might even have avoided the common misconception that Dawkins was advocating individual selfishness.
In the end, it was Michael Rodgers of Oxford University Press who enthusiastically published The Selfish Gene, after demanding “I must have that book!” when he saw early draft chapters.
Dawkins wrote a small program to illustrate the effects of natural selection that came with the book. It was quite clever. It displayed a few dozen versions of some animal, say a bird, and you clicked on the one you like. You then got a few dozen modifications of your choice and could make another selection. Eventually you got something quite different.
The program ran on a Mac of several generations ago. To my knowledge, it has never been upgraded to the newer Macs. Someone should do it.
It was called “Biomorphs”. There is an online implementation.