Scientists find host of antibiotic-eating germs

Friday, April 4th, 2008

Scientists find host of antibiotic-eating germs:

A study of soil microbes taken from 11 sites uncovered bacteria that could withstand antibiotics 50 times stronger than the standard for bacterial resistance.

“It certainly was very surprising to us,” said George Church, a geneticist at Harvard Medical School in Boston, whose research appears in the journal Science.

“Many bacteria in many different soil isolates can not only tolerate antibiotics, they can actually live on them as their sole source of nutrition,” Church said in an audio interview on the journal’s Web site.
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Church’s team initially set out to find organisms in the soil that remove toxins from cellulose, the material that gives plants structure. They took samples from a variety of sites, including a cornfield fertilized by manure from cows that were fed antibiotics.

Microbes taken from these soil samples could easily defeat toxins from cellulose, which they expected. Then the researchers tested the microbes against antibiotics, something they thought would be toxic.

“We were expecting them to grow on cellulose and we weren’t expecting them to grow on antibiotics,” Church said.

Surprised by how easily the microbes devoured the antibiotics, Church and colleagues did a broader test, exposing hundreds of microbes to 18 antibiotics representing most of the major classes of naturally occurring and synthetic antibiotics, including penicillin and the widely prescribed antibiotic ciprofloxacin.

“We could find … bacteria that could grow on almost all of them,” depending on the bacteria and the source of the soil, Church said.

Scared yet?

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