Halloween came early

October 24th, 2019

Something Wicked This Way Comes by Ray BradburyRay Bradbury wrote a screenplay in 1958, intended as a directorial vehicle for his friend Gene Kelly. Financing for the project never came through though, and Bradbury converted the screenplay into a novel, Something Wicked This Way Comes, which was published in 1962. It opens with this prologue:

First of all, it was October, a rare month for boys. Not that all months aren’t rare. But there be bad and good, as the pirates say. Take September, a bad month: school begins. Consider August, a good month: school hasn’t begun yet. July, well, July’s really fine: there’s no chance in the world for school. June, no doubting it, June’s best of all, for the school doors spring wide and September’s a billion years away.

But you take October, now. School’s been on a month and you’re riding easier in the reins, jogging along. You got time to think of the garbage you’ll dump on old man Prickett’s porch, or the hairy-ape costume you’ll wear to the YMCA the last night of the month. And if it’s around October twentieth and everything smoky-smelling and the sky orange and ash gray at twilight, it seems Halloween will never come in a fall of broomsticks and a soft flap of bedsheets around corners.

But one strange wild dark long year, Halloween came early.

One year Halloween came on October 24, three hours after midnight.

I had been meaning to read the novel for years — ever since watching the mediocre film adaptation — so I finally listened to the audiobook. The mediocre movie was mediocre despite the fact that Bradbury wrote the screenplay. It’s only available on DVD, as far as I can tell.

More recently, “Something Ricked This Way Comes” parodied…Stephen King’s Needful Things, which was inspired by Something Wicked.

Find another man who is kinder and stronger to stand in the way

October 23rd, 2019

In 2015, two years after graduating from university, :

In one session, we asked the women to make an A3 map of their lives from torn-up magazines. The collage would show a road that meandered from their past experiences to future goals. Almost every road began with bottles of vodka, syringes and shadowy characters, and almost every one ended with symmetrical houses and white wedding dresses and Laura Ashley sofas. I had spiked the magazine pile with my partner’s railway-modelling magazines and glossy Sunday supplements in the hope of inspiring something different — a new job, an interesting hobby, some travel, perhaps? — but to little avail.

[...]

“It will be finding ‘the one’ that will get me out of my mess,” she said. “He will look after me and keep people away who come round trying to sell me gear [heroin] again.”

Cathy’s was an oft-told story. She had been prevented from seeing her children by social services because she couldn’t stop seeing an abusive partner. He kept coming round and, against her best judgment, she opened the door.

What I wanted to say was that she didn’t need a man to straighten her life out for her, that she had “everything she needed inside of her” (life advice that works best when Instagrammed over a picture of a thin white girl walking into a sunset).

In time I came to realise that she was probably right. Ambition and independence are a good deal further up the hierarchy of need than security. It’s pretty realistic to assume that the quickest way to ward off a coercive and abusive man is to find another man who is kinder and stronger to stand in the way.

It would be frighteningly easy to have much larger wars than any we have ever seen in history

October 22nd, 2019

In Only the Dead: The Persistence of War in the Modern Age Ohio State University professor of political science Bear Braumoeller argues that war is not declining:

Braumoeller used the Correlates of War data set, which scholars from around the world study to measure uses of force up to and including war.

What he found with the statistical analyses was that any decline in the deadliness of war that we think we see in the data is within the normal range of variation — in other words, our period of relative peace right now could easily be occurring simply by chance.

[...]

Once an armed conflict has had more than 1,000 battle deaths (the criteria for being included in the Correlates of War database), there’s about a 50 percent chance it will be as devastating to combatants as the 1990 Iraq War, which killed 20,000 to 35,000 fighters.

There’s a 2 percent chance — about the probability of drawing three of a kind in a five-card poker game — that such a war could end up being as devastating to combatants as World War I. And there’s about a 1 percent chance that its intensity would surpass that of any international war fought in the last two centuries.

“This is pretty bleak. Not only has war not disappeared, but it would be frighteningly easy to have much larger wars than any we have ever seen in history,” Braumoeller said.

There was all this complexity that we couldn’t ignore

October 21st, 2019

Patricia Marcoccia and Maziar Ghaderi decided to make The Rise of Jordan Peterson before he became controversial:

She’d become interested in his work while she was a college student studying psychology at McMaster University back in the early 2000s. “I found his work on the psychology of meaning very impactful,” she explains. “And I knew he was having a big impact on his students over in Toronto, too.” After graduating and shifting her focus to journalism and film, she decided that she wanted to make Peterson the focus of her first independent feature. She approached him about it in 2015.

After learning more about Peterson’s personal life, Marcoccia decided to focus on his friendship with Charles Joseph, an accomplished third-generation Kwakwaka’wakw carver/artist. A year-and-a-half into that project, she awoke one morning to find that Peterson had posted “Professor Against Political Correctness” on YouTube and that all hell had broken loose. “The video was a total surprise to me. I had no idea it was coming,” she says. “I’d been filming conversations about dreams, Charles carving masks and totem poles, and a sacred potlatch ceremony” — Peterson and his family were at the time immersed in a very involved process of being ceremonially inducted into Joseph’s extended family — “and all of a sudden, there was all this conflict and controversy.”

After a few weeks, Marcoccia decided that she needed to change the focus of her film, and follow the rapidly developing story on which, unexpectedly, she had a uniquely privileged perspective. At the time, neither she nor her husband, a multimedia artist who was now working with her on the film, felt particularly happy about this switch. “This wasn’t the ambulance we would have been chasing” had circumstances been different, she explains. “We didn’t feel comfortable dealing with the ‘free speech versus transphobe’ controversy. But we also didn’t see walking away as an option. You need to follow a film where it takes you.”

“There was so much of this culture war stuff that we didn’t understand,” Ghaderi reflects. Personally and professionally immersed in the left-leaning worlds of art, film, and theater, working with his wife on the documentary when everything “suddenly blew up” was “confusing.” Marcoccia and Ghaderi agreed that if they hadn’t known Peterson and his work personally, and had only read about him in the media outlets they normally digested, they would have most likely been swept up in the anti-Peterson sentiment that dominated their milieu. Instead, they became hyper-aware that “there was all this complexity that we couldn’t ignore.”

Marcoccia and Ghaderi watched — and filmed — as activists, journalists, bloggers, fans, and even their close friends, rather than acknowledging this complexity, turned Peterson into a dichotomous “messiah/devil” icon. “There are right-wing opportunists who want to use Jordan for their own political ends,” Ghaderi notes. “There are people who want to use him to fill the gap of not having a father. There are the Antifa types who condemn him while they’re wearing a mask. It’s the media — journalists, writers, bloggers — that create Jordan’s persona.” The film’s official poster symbolically illustrates that these many competing forces collude to create a false image of the man they’ve come to know.

If the respect that the Marcoccia and Ghaderi have for Peterson is obvious, it’s also unexceptional. That respect extends to all their subjects, including a trans activist who criticizes them for making the film at all. As their website explains, they named their company “Holding Space Films” because the concept of holding space “is central to the filmmaking process”:

To hold space for someone is to metaphorically walk with them amidst their experience using genuine presence and deep listening to enable authenticity to emerge.

Rather than sorting their interviewees into partisan boxes, the filmmakers engage sympathetically with the multidimensional complexity of everyone involved. The consistency of Marcoccia and Ghaderi’s method constitutes a critical theme throughout the film. It’s what enables the (open minded) viewer to experience the nuances under investigation as thought provoking, rather than merely confusing. The people, issues, and events may sometimes be abstruse, but the unpretentious clarity of the filmmakers’ method results in a film that is intelligible, accessible, engaging, and coherent.

It’s important to note that “holding space” in the sense Marcoccia and Ghaderi mean it is difficult. It’s not easy to remain steady in the midst of intense conflict, and listen to the different sides involved with curiosity, empathy, and respect — let alone capture that in a 90-minute film. That they have largely succeeded is a significant accomplishment; one that’s much needed and all too rare. It requires a disciplined commitment to a deeply humane sensibility, an ethos that is widely misunderstood and ignored, if not denigrated and attacked today.

Naturally, it’s being shut out of independent and arthouse cinemas.

China will spend money and endure a dirty industry

October 20th, 2019

Coal-burning China’s embrace of electric vehicles may also be more about money than the environment:

China produces less than 5% of the world’s oil — used in combustion engines — but about 45% of the globe’s coal, used in electricity production for EVs. In much the way that the U.S. is the world’s largest user of homegrown crops for motor fuel despite widespread criticism of ethanol subsidies as costly and environmentally damaging, China will spend money and endure a dirty industry to be energy independent as well.

More than that, though, Beijing wants to dominate tomorrow’s car industry. China’s opening to the West came too late for it to be a major exporter of internal combustion engine vehicles, but it has made aggressive moves to dominate battery production, including securing sources of key metals. Through lavish subsidies it already has by far the world’s largest domestic EV market.

Doesn’t that sound laissez unfair?

October 19th, 2019

The March of History pits Mises vs. Marx in a Hamilton-esque rap battle:

Workers of the world — ASSEMBLE!
It’s time for the ruling classes to tremble.
I’m the people’s hero, the MVP:
M – A – R – X! Yeah, you know me!

Let’s go back to when men were free.
We hunted and gathered communally.
But get ready, ’cause here comes the twist,
A villain appears, called a “capitalist”.

He puts the proletariat — that’s US — in chains,
exploits our labor, and pockets the gains.
Though slick ads he trick lads and ladies in kind,
selling fake needs he poisons our hearts and minds.

He rots our soul through alienation
pursuing limitless accumulation.
He works us into an early grave,
through debt, steals back the money we save.

Greed is the gospel! Profit? GOD.
The rich get richer through graft and fraud.
The poor get poorer, but YOU don’t care.
Doesn’t that sound laissez unfair?

200 years I’ve been singing this song,
Now my chorus is 99% strong.
The revolution’s here. It’s time to repent.
Your moment is over — your capital’s SPENT!

Who’s paying attention to the prey?

October 18th, 2019

In The Crime Fighter, Jack Maple, one time New York City Transit Police officer and later Deputy Commissioner of NYPD, describes how he would spot criminals:

He would simply look for “prey”, and then look for who was paying attention to the “prey”. In short, he had to think like a criminal.

10 major areas that modern military forces choose to ignore

October 17th, 2019

Carlton W. Meyer lists 10 major areas that modern military forces choose to ignore:

1. The lethality of of precision guided munitions to easily destroy ultra-expensive ships, tanks, and aircraft has been dismissed.

2. The use of small lasers to blind combatants. The US Marine Corps recently added expensive “dazzlers” to its machine guns that will prove more effective than the gun itself.

3. The inability to replace munitions stocks in a timely manner. Most nations have limited stockpiles and the complexity of some make rapid production impossible. If the USA becomes involved in a major war that lasts longer than a month, it will have to pause for several months until new munitions are produced and delivered.

4. The humanitarian disaster that would result by disrupting the fragile economy of megacities. This occurred during World War II, but today’s big cities are ten times larger! Armies may face hoards of millions of starving people begging for help.

5. The millions of civilian vehicles on the world’s roads. It is impossible to tell if they are friend or foe unless inspected up close. Soldiers can use this to their advantage, which makes urban operations very dangerous for both civilians and soldiers.

6. The problem of thousands of commercial aircraft roaming the globe. Agents aboard can collect intelligence and these present long-range targeting problems for precision guided munitions that may kill hundreds of innocents.

7. Adding warheads to inexpensive, commercial, hobbyist UAVs create deadly “suicide micro-drones.”

8. Modern anti-tank weapons are equally effective anti-aircraft weapons against slower targets like low flying helicopters and aircraft transports. A helicopter assault or airborne drop near a modern army will be disastrous as anti-tank missiles shoot upwards and knock down aircraft.

9. Modern body armor has made 5.56mm and even 7.62mm bullets less lethal.

10. Fleets of surface ships cannot hide for long in big oceans.

(Hat tip to commenter Sam J.)

A Nobel-winning economist goes to Burning Man

October 16th, 2019

Economist Paul Romer went to Burning Man:

It was the first time that Mr. Romer, the former chief economist of the World Bank, had attended the annual bacchanal.

A week earlier, there was hardly anything here, in the remote desert of northwest Nevada. Then tens of thousands of people had just shown up, many in the middle of the night. They had formed an instant city, with a road network, and a raucous street life, and a weird make-do architecture.

[...]

To economists, cities are labor markets. And labor markets can’t function when there are no roads leading workers out of their favelas, or when would-be inventors never meet because they live in gridlock.

Mr. Romer’s answer is to do with this moment what Burning Man does every summer: Stake out the street grid; separate public from private space; and leave room for what’s to come. Then let the free market take over. No market mechanism can ever create the road network that connects everyone. The government must do that first.

[...]

Most of the structure that has been added since feels invisible to the people who come: the streets that are surveyed to be exactly 40 feet wide, the plazas that steer people together without crowding them, the 430 fire extinguishers around town, each tracked by its own QR code.

[...]

After 1996, the founders also began putting up a fence around the city, a pentagon with perfectly straight sightlines. Nominally, it is a “trash fence,” catching debris before it blows into the desert. But it also defines the edge of the city, so that it is possible to stand at the boundary line and stare out into an open desert uncluttered by tents or plywood art. The fence is an urban growth boundary. It is as much about keeping out interlopers as keeping people in.

The best offenses use the width and the depth of the field

October 14th, 2019

NFL offenses averaged more points per possession and yards per play last year than ever before by challenging defenses to cover the entire football field:

Fifty years ago, college football was upended by an idea that began this way of thinking. It was a formation called the wishbone. Texas used it to win 30 consecutive games, and other powerhouses like Alabama and Oklahoma soon followed en route to national championships of their own.

The wishbone was based on the concept of the triple-option. A quarterback could hand off, run the ball himself, or later pitch it to another running back. Passing was a rarity. But this antiquated offense was also futuristic: it took advantage of the vast width of a football field. Running was no longer limited to a singular direction. Defenders had to make a choice between going after the guy with the ball, or the one who would later receive it.

But the wishbone shunted another dimension. Because passing was such an afterthought, wishbone teams didn’t push the ball vertically. When Texas went undefeated in 1969, the Longhorns ran for 3,630 yards and passed for only 1,091.

“The best offenses use the width—and the depth of the field,” McVay says.

Other scheming minds looked for an edge by revolutionizing the passing game. The “West Coast Offense,” which Bill Walsh used to win three Super Bowls with the San Francisco 49ers, attacked the edges of the field with a preponderance of higher percentage, shorter-length passes. Observers likened it to reconstructing the running game into a passing attack.

Other twists opened up the vertical element. In 1980, the Chargers broke the NFL record for most passing yards in a season, and by 1985 they had five of the six most prolific passing years ever. They did it with a self-explanatory offense called “Air Coryell.” Their coach, Don Coryell, wanted to air the ball as far down field as frequently as possible.

Still, there was a lingering question: how could an offense attack defenses in every direction on every play? The solution was hiding in plain sight—in college football. It just took shockingly long to trickle up to the pros.

In 2000, the same season the Ravens won the Super Bowl with one of the best defenses in NFL history, something far more important happened: Northwestern won a bunch of football games. The Wildcats didn’t invent the spread offense, but when a bunch of eggheads started using it to topple powerhouses, the whole football world had to pay attention. They beat No. 7 Wisconsin, thumped No. 18 Michigan State and then toppled No. 12 Michigan 54-51 in a nationally televised thriller.

“I saw them almost scoring at will,” Michigan coach Lloyd Carr said afterward.

Variations of the spread proliferated across college football. Teams lined up wide on every play with four or five receivers. They played almost exclusively out of the shotgun. The most radical teams adopted an extreme version known as the “Air Raid,” which played at hyperspeed and eschewed the idea of striking a balance between running plays and passing plays.

[...]

In 2001, NFL teams used the shotgun on just 14% of plays, according to Football Outsiders. In 2006, it was still just 20%. By last season, that had skyrocketed to 64%. [...] The Chiefs lined up in the shotgun on 81% of snaps last year.

A few years ago, Michael Lewis, author of Moneyball, looked at Texas Tech’s unorthodox offense.

Half of Americans read a book in the last year

October 13th, 2019

The size of the American reading public varies depending on one’s definition of reading:

In 2017, about 53 percent of American adults (roughly 125 million people) read at least one book not for school or for work in the previous 12 months, according to the National Endowment for the Arts (NEA). Five years earlier, the NEA ran a more detailed survey, and found that 23 percent of American adults were “light” readers (finishing one to five titles per year), 10 percent were “moderate” (six to 11 titles), 13 percent were “frequent” (12 to 49 titles), and a dedicated 5 percent were “avid” (50 books and up).

Go anywhere and land anywhere quickly and quietly

October 12th, 2019

Kitty Hawk’s HVSD — or Heaviside, after renowned physicist and electrical engineer Oliver Heaviside — is an electric aircraft designed to go anywhere and land anywhere quickly and quietly:

The aircraft is 100 times quieter than a helicopter, the pair said. And it’s faster. Thrun says HVSD, which has a range of about 100 miles, can travel from San Jose to San Francisco in 15 minutes. The aircraft can be flown autonomously or manually, but even then most of the tasks of flying are handled by the computer, not the human.

Moments after walking around HVSD, the decibel meter, still in Thrun’s grasp, gets put to work. A helicopter that is stationed about 150 feet from where we’re standing is fired up. After two minutes, the helicopter lifts off, its whop-whop-whop lingering even as the craft is more than 600 feet in the air and begins its circular flight path around the testing area. The meter pops above 85 decibels and stays there for several minutes. The decibels go beyond 88 decibels at landing.

Later, after the helicopter lands and the engine slowly winds down, the test turns to HVSD.

An engineer, who is standing in an open air tower, brings HVSD suddenly to life. Unlike a helicopter, the HVSD starts and lifts off in just seconds. There is sound as it lifts off — hitting about 80 decibels — but what’s striking is the brevity. The take-off sound lasts fewer than 10 seconds. As HVSD gains altitude and then circles above us, the only sound is a few engineers and technicians talking nearby.

Once Thrun quiets the crew, the noise falls below 40 decibels, which is what a typical, quiet residential neighborhood registers at. HVSD is nearby at about 600 feet of altitude, but it is barely audible as it circles above us. An office with an air conditioning running might be about 50 decibels, Thrun says for comparison.

“The calculus here is that this has to be socially acceptable for people,” Thrun says. “There’s a reason why helicopters are not: they’re for rich people and they’re noisy.”

(Hat tip to Hans G. Schantz, whose Hidden Truth novels feature Heaviside.)

A tank or fighter jet is prized not for its practical utility

October 11th, 2019

American defense experts who come to the island all agree that the Taiwanese military needs cheap, expendable, mass-produced weapons systems to deter a Chinese invasion force, but that’s not what Taiwanese leaders buy:

On June 6, Taiwan’s Ministry of National Defense announced a $2.25 billion arms purchase from the United States. package was broken down into two parts: $250 million for a consignment of Stinger missiles, and $2 billion for 108 main battle tanks. The first part of the package fits well enough within a distributed “anti-access” defense posture. The second purchase does not.

Taiwan is a piebald of jungle-covered mountains, muddy rice paddies, and densely populated urban cores—terrain that frustrates tank maneuver. The most likely use for tanks like these would be in formation near beaches for counter-landing operations, where they would be extremely vulnerable to attack from the air. As Chinese commanders would never land an invasion force unless they first secure air superiority, these tanks will never amount to anything more than 108 very expensive sitting ducks.

The purchase fits a longstanding Taiwanese pattern: prioritizing high-prestige platforms over people. The Ministry of National Defense has cut military pensions and failed to pay volunteer soldiers a competitive wage or provide them with necessary benefits, and it doesn’t have enough bullets on hand for conscripts to practice riflery more than a few times in their entire course of duty.

Yet in addition to buying the tanks, President Tsai Ing-wen’s administration has promised to find $8 billion—equivalent to 70 percent of Taiwan’s 2019 military budget—to purchase 66 new F-16 fighter jets (even though in the event of a conflict with China most of these would be destroyed by PLA missiles while still on their runways). The Taiwanese navy also regularly promotes plans for an indigenously constructed helicopter carrier and Aegis-style destroyer. Billions have been poured into developing indigenous jet engines and fighters. Most disastrous of all, around one-tenth of the defense budget has been earmarked for the development of Taiwan’s indigenous submarine program. According to the wildly optimistic government projections, the very first of these submarines will be seaworthy in 2025. Only a few more could be built before the decade’s close, at an estimated $1 billion per ship.

Taiwanese leaders’ defense priorities make a perverse sort of sense, T. Greer argues:

Taiwanese leaders have a powerful political incentive to raise Taiwan’s stature on the international stage and publicly resist Chinese attempts to cut it away from its allies. Similarly, they are incentivized to show that under their leadership, the Taiwanese military remains a world-class fighting force. Purchasing fancy military equipment makes little strategic sense, but it accomplishes both of these objectives.

In an anonymous interview, one DPP official told me why he believed the purchase of the tanks was so important: “The purchase is a signal that the DPP can lead on defense. It will give the people more confidence that we are not being outclassed by the Chinese. And most important, that Tsai’s good relationship with the Americans is the reason for that.” A senior official interviewed by a Center for Security Policy Studies research team justified Taiwanese requests for F-35 fighter jets, rather than less expensive drones, with similar logic: “You can’t create a hero pilot of a UAV.” The CSPS team concluded that for most of the Taiwanese officials they interviewed, “buying advanced aircraft from the United States was at least as much about assuring the public as it was about improving war-fighting capability.”

This is especially important given Taiwan’s lack of a formal alliance with the United States. For Taiwanese leaders, weapons sales are one of the few metrics available to judge the U.S. commitment to their cause. Taiwanese leaders can trumpet their purchase of American-made weapons systems as something their party has done to raise Taiwan’s international stature. A tank or fighter jet is prized not for its practical utility but its symbolic value.

The brain seems to be wired to be periodically distractible

October 10th, 2019

To pay attention, the brain uses filters, not a spotlight:

For a long time, because attention seemed so intricately tied up with consciousness and other complex functions, scientists assumed that it was first and foremost a cortical phenomenon. A major departure from that line of thinking came in 1984, when Francis Crick, known for his work on the structure of DNA, proposed that the attentional searchlight was controlled by a region deep in the brain called the thalamus, parts of which receive input from sensory domains and feed information to the cortex. He developed a theory in which the sensory thalamus acted not just as a relay station, but also as a gatekeeper — not just a bridge, but a sieve — staunching some of the flow of data to establish a certain level of focus.

[...]

[Michael Halassa, a neuroscientist at the McGovern Institute for Brain Research at the Massachusetts Institute of Technology] was drawn to a thin layer of inhibitory neurons called the thalamic reticular nucleus (TRN), which wraps around the rest of the thalamus like a shell. By the time Halassa was a postdoctoral researcher, he had already found a coarse level of gating in that brain area: The TRN seemed to let sensory inputs through when an animal was awake and attentive to something in its environment, but it suppressed them when the animal was asleep.

In 2015, Halassa and his colleagues discovered another, finer level of gating that further implicated the TRN as part of Crick’s long-sought circuit — this time involving how animals select what to focus on when their attention is divided among different senses. In the study, the researchers used mice trained to run as directed by flashing lights and sweeping audio tones. They then simultaneously presented the animals with conflicting commands from the lights and tones, but also cued them about which signal to disregard. The mice’s responses showed how effectively they were focusing their attention. Throughout the task, the researchers used well-established techniques to shut off activity in various brain regions to see what interfered with the animals’ performance.

As expected, the prefrontal cortex, which issues high-level commands to other parts of the brain, was crucial. But the team also observed that if a trial required the mice to attend to vision, turning on neurons in the visual TRN interfered with their performance. And when those neurons were silenced, the mice had more difficulty paying attention to sound. In effect, the network was turning the knobs on inhibitory processes, not excitatory ones, with the TRN inhibiting information that the prefrontal cortex deemed distracting. If the mouse needed to prioritize auditory information, the prefrontal cortex told the visual TRN to increase its activity to suppress the visual thalamus — stripping away irrelevant visual data.

The attentional searchlight metaphor was backward: The brain wasn’t brightening the light on stimuli of interest; it was lowering the lights on everything else.

[...]

With tasks similar to those they’d used in 2015, the team probed the functional effects of various brain regions on one another, as well as the neuronal connections between them. The full circuit, they found, goes from the prefrontal cortex to a much deeper structure called the basal ganglia (often associated with motor control and a host of other functions), then to the TRN and the thalamus, before finally going back up to higher cortical regions. So, for instance, as visual information passes from the eye to the visual thalamus, it can get intercepted almost immediately if it’s not relevant to the given task. The basal ganglia can step in and activate the visual TRN to screen out the extraneous stimuli, in keeping with the prefrontal cortex’s directive.

[...]

Halassa’s findings indicate that the brain casts extraneous perceptions aside earlier than expected. “What’s interesting,” said Ian Fiebelkorn, a cognitive neuroscientist at Princeton University, is that “filtering is starting at that very first step, before the information even reaches the visual cortex.”

[...]

According to his findings, the focus of the attentional spotlight seems to get relatively weaker about four times per second, presumably to prevent animals from staying overly focused on a single location or stimulus in their environment. That very brief suppression of what’s important gives other, peripheral stimuli an indirect boost, creating an opportunity for the brain to shift its attention to something else if necessary. “The brain seems to be wired to be periodically distractible,” he said.

It’s a very vulnerable point, and plants have targeted it

October 9th, 2019

Monarch butterflies eat only milkweed, a poisonous plant that should kill them, and even store the toxins in their own bodies as a defense against hungry birds:

Only three genetic mutations were necessary to turn the butterflies from vulnerable to resistant, the researchers reported in the journal Nature. They were able to introduce these mutations into fruit flies, and suddenly they were able to eat milkweed, too.

[...]

Insects began dining on plants over 400 million years ago, spurring the evolution of many botanical defenses, including harsh chemicals. Certain plants, including milkweed, make particularly nasty toxins known as cardiac glycosides.

The right dose can stop a beating heart or disrupt the nervous system. For thousands of years, African hunters have put these poisons on the tips of arrows. Agatha Christie wrote a murder mystery featuring foxglove, which produces cardiac glycosides.

The toxins gum up so-called sodium pumps, an essential component of all animal cells. “It’s a very vulnerable point, and plants have targeted it,” said Susanne Dobler, a molecular biologist at the University of Hamburg in Germany.

These pumps move positively charged sodium atoms out of cells, giving their interiors a negative charge. Heart cells need sodium pumps to build enough electrical charge to deliver a heartbeat. Nerves use the pumps to produce signals to the brain. If the pumps fail, then those functions come to a halt.

[...]

The researchers compared the genes that serve as blueprints for the sodium pump in poison-resistant species, like the milkweed beetle and the milkweed bug. Most of these species, it turned out, had gained the same three mutations.

[...]

Monarchs share one of the mutations with a related butterfly that doesn’t eat milkweed, and a second mutation with a closer relative that eats milkweed but doesn’t store cardiac glycosides in its wings. The third mutation arose in an even more recent ancestor.

Gaining these mutations gradually altered the sodium pumps in the monarchs’ cells, Dr. Dobler suspected, so that the cardiac glycosides couldn’t disrupt them. As the butterflies became more resistant, they were able to enjoy a new supply of food untouched by most other insects.

[...]

Noah Whiteman, an evolutionary biologist at the University of California, Berkeley, led the effort to test this hypothesis. “These three mutations may be the thing that unlocked the door” for the butterflies, he said.

He and his colleagues figured out how to use Crispr, the gene-editing technology, to introduce the mutations into fruit flies. The flies survive on rotting fruit, and even a small dose of cardiac glycosides can be deadly to them.

The researchers began by giving the flies the first mutation to arise in the ancestors of monarchs. The larvae that carried this mutation were able to survive on a diet of yeast laced with low levels of cardiac glycosides.

The second mutation let the flies withstand even more toxins, and the third made them entirely resistant. With all three mutations, the flies even ate dried milkweed powder.

The third mutation had another striking effect. When the flies with the gene developed into adults, their bodies carried low levels of cardiac glycoside, useful as a defense against predation.

O brave new world that has such insects in it!