Steroids boost performance in just weeks

Friday, August 13th, 2004

New Scientist recently produced a a study demonstrating that fairly low doses of anabolic steroids boost performance in just weeks:

The first rigorous study of the performance-enhancing effects of testosterone in young men was not carried out until 1996. Volunteers were given weekly injections of either 600 milligrams of testosterone enanthate or a placebo for 10 weeks (bodybuilders usually take much larger doses). Performance tests done at the end of this period showed the hormone had improved muscle size and strength in those doing strength training, and to a lesser extent in those who did not exercise.
[...]
In the latest study, Weatherby monitored the performance of 18 male amateur athletes over a six-week training regime. Nine were given weekly shots of testosterone enanthate at a dose of 3.5 milligrams per kilogram of body weight for six weeks (equivalent to roughly half the dose of the 1996 trial), and nine were given a placebo.
[...]
The most unexpected finding was that the greatest increases in muscle size and power occurred just three weeks into the trial.

An Olympian Task

Friday, August 13th, 2004

Supercomputers are being used to analyze swimming mechanics:

Mr. Mark donated the Rose and Krayzelburg scans, and a set of videos from USA Swimming’s flume in Colorado Springs. One showed Ms. Coughlin dolphin-kicking. When he saw it, Prof. Mittal knew she was the swimmer he had to use.

“She swam straight, maintaining an even depth,” he says. “All fish do this, passing a wave through their bodies from head to tail. This was it — the natural-selection stroke, the best way to swim.”

Lacking a scan of Ms. Coughlin, Prof. Mittal assigned a student to superimpose her videoed body, frame by frame, onto the scan of Ms. Rose. He then asked James Hahn, director of GWU’s Institute for Computer Graphics, to essentially insert a skeleton, enabling the scan to move. The output is a goggled, silver phantom, dolphining across a black screen, trailing a thin red line undulating across a graph — sort of like the markings on an electrocardiogram.

Three-dimensional, observable from all angles, this creature is Prof. Mittal’s raw material. All he has to add next is water. Pushing the limits of his field-computational fluid dynamics, he plans to factor in every swirl and counterswirl produced by an ever-changing sequence of motions known as a single stroke. To account for every eddy within every eddy, he will break each stroke into 20,000 units and perform 200 million calculations on every one.

One Giant Lift for Mankind

Tuesday, August 10th, 2004

In One Giant Lift for Mankind, Josh Levin describes “the race for the 1,000-pound bench press”:

For years, the bench press world record crept up slowly and steadily. In the 1950s, Canadian Doug Hepburn became the first man to bench 400, 450, and 500 pounds. In 1957, Hepburn told Muscle Power magazine that a 600-pound bench press was possible, but it wasn’t until 1967 that Pat Casey cracked that barrier. Ted Arcidi broke 700 in 1985, and it took another 17 years until Ryan Kennelly benched 800 pounds in 2002. Now, just two years later, 10 men have benched 800, and a couple are closing in on 1,000. So, why have records that stood up to the strongest men in the world for 50 years crumbled in the last two?

A super-shirt, mostly. In 1983, a college student and powerlifter named John Inzer started making shirts that supported benchers’ shoulders and deltoids. Word spread that the bench shirt not only prevented injuries but actually helped bounce the weight off your chest. The terminology on Inzer’s web site reeks of pseudoscience — the top-of-the-line Inzer Phenom shirt “features the EVS (Escape Velocity System) built inside” — but the shirt’s effect is undeniable. As the record for the shirted bench press shot up to 965 pounds, the unshirted or “raw” mark has stayed at an earthly 713 pounds. (Scot Mendelson has that record.) Nowadays, every top bench-presser uses the shirt for safety and power. “The whole raw thing, you’re just asking for trouble if you’re going to be dealing with any kind of weight,” says Ryan Kennelly. “If you rip your pec, you rip your rotator cuff, you’re out of there. Thank God for bench shirts.”

The bench shirt — which comes in denim or polyester — has arms that jut out zombielike, perpendicular to the chest. The position is so awkward and the fit so tight that lifters typically need help swaddling themselves. As the bar starts to press the weightlifter’s arms down, a percentage of the load goes to deforming the shirt. High-end shirts are so taut that for the bar to even reach a bencher’s chest, the fabric has to be compressed with incredible force. (At one meet, Rychlak had to abandon an 890-pound lift because it wasn’t heavy enough to force the weight down to his pecs.) When the bencher starts to push the bar back up, the shirt acts like a spring. As the material snaps back to its original, zombie-arm orientation, the lifter’s elbows get a bit of extra help moving the weight back into the air.

Inzer says the bench shirt “brings out the deeper strength of a lifter.” Powerlifting traditionalists and scientists think the opposite.

As the record for the shirted bench press shot up to 965 pounds, the unshirted or “raw” mark has stayed at an earthly 713 pounds. I feel so very, very weak.

Olympic Wrestling Timeline

Monday, August 9th, 2004

TheMat.com‘s Olympic Wrestling Timeline offers some interesting trivia:

1896 – Athens, Greece

The first modern Olympics was held in Athens, Greece, home of the ancient Olympics. Wrestling, one of the featured sports of the ancient Games, was included in the program of the first modern Olympics. The style was Greco-Roman, and just one weight class was contested, heavyweight. Karl Schumann of Germany became the first Olympic wrestling gold medalist. No U.S. wrestlers participated in the Athens Games.

1900 – Paris, France

Wrestling was not included in the program at the 1900 Olympics, the only time during the modern Games that wrestling was not a featured sport.

1904 – St. Louis, Mo.

The first of the modern Olympic Games held in the United States featured freestyle wrestling, a style that was popular in the United States. The U.S. was the only nation entered in wrestling and scored a clean sweep of all the wrestling medals, with seven golds, seven silvers and seven bronzes.

1906 – Athens, Greece

Athens became the first city to host more than one modern Olympic Games. Greco-Roman wrestling, more popular than freestyle in Europe, was the featured style, and freestyle was not included. Three Greco-Roman champions were crowned, and the United States did not participate in wrestling event.

1908 – London, England

The London Olympics featured both of the international wrestling styles for the first time, freestyle and Greco-Roman. The United States dominated the freestyle light weights, with George Mehnert claiming the 119-pound title and George Dole capturing the 132.5-pound event. For Mehnert, it was a second career Olympic title. It would be another 84 years before an American wrestler would win a second Olympic gold medal, when John Smith and Bruce Baumgartner claimed second titles in Barcelona. Mehnert was a club wrestler from Newark, New Jersey, while Dole, who competed at Yale, helped establish the tradition of college wrestlers moving on to Olympic glory.

Greco-Roman was dominated by European nations, and the United States did not participate.

1912 – Stockholm, Sweden

Greco-Roman, the favored style of the Scandinavian nations, was the only wrestling event in Stockholm, and the gold medals went to athletes from either Finland or Sweden. The United States entered athletes, but did not medal.

Eating Lots of Carbs May Raise Cancer Risk

Friday, August 6th, 2004

Eating Lots of Carbs May Raise Cancer Risk reports on a recent Mexican study linking breast cancer to carb consumption:

Scientists think carbs may increase cancer risk by rapidly raising sugar in the blood, which prompts a surge of insulin to be secreted. This causes cells to divide and leads to higher levels of estrogen in the blood, both of which can encourage cancer.

A study earlier this year suggested that high-carb diets modestly raised the risk of colon cancer. Little research has been done on their effect on breast cancer, and results have been mixed. One study last year found greater risk among young women who ate a lot of sweets, especially sodas and desserts.

For this study, researchers enrolled 475 women newly diagnosed with breast cancer and a comparison group of 1,391 healthy women in Mexico City who were matched for age, weight, childbirth trends and other factors that affect the odds of getting the disease.

Women filled out a lengthy food questionnaire developed by Willett and widely used in nutrition studies, and were divided into four categories based on how much of their total calories came from carbohydrates.

Those in the top category — who got 62 percent or more of their calories from carbs — were 2.22 times more likely to have breast cancer than those in the lowest category, whose carb intake was 52 percent or less of their diet.

At-Home Workouts Move From TV to Computer

Wednesday, August 4th, 2004

Fitness gurus are starting to provide interactive workout videos over the Net. From At-Home Workouts Move From TV to Computer:

Thanks to the proliferation of broadband and advances in Internet video technology, a number of companies are starting to offer online fitness classes with the aim of providing exercisers with instant variety — and, sometimes, an interactive experience.

The Yoga Learning Center, where Ms. Hitchcock takes her classes, offers about 50 online video and audio yoga practices and meditations, double the amount it launched with in October 2003. Customers pay $9.95 a month for unlimited access. The center is adding at least one new class each month and, by next year, plans to expand into Pilates.

Meanwhile, New York Yoga, which has offered live, online yoga classes from its New York studios since March 2001, expanded into prerecorded streaming-video classes in December. The site now offers 60 live classes throughout the week and 21 prerecorded sessions. Joining the online studio starts at $7.95 a month.

Beyond yoga, a new site called Daily Fitness is set to launch later this summer with six streaming video classes, including kickboxing, step aerobics and belly dancing. The site will also offer personal training and nutrition sessions, via video teleconference. A base membership is expected to cost about $14.95 a month and training sessions around $35 to $40 an hour.

The Real Olympics

Wednesday, August 4th, 2004

I recently managed to stumble upon PBS’s The Real Olympics:

No event in the ancient world can be compared to the Olympic Games, held every four years and without interruption for nearly 12 centuries. The games drew tens of thousands of people from Greek colonies along the length of the Mediterranean and the shores of the Black Sea when Greek culture and influence were at their height.

[...]

The games were almost 800 years old when Jesus Christ was born, and it took a special Christian edict to stop them, four centuries after his death. Abandoned and long forgotten, they would return in the modern age as the inspiration for the most prestigious sport event on earth.

The first episode — which I didn’t catch in full — “reveals how the ancient games have been appropriated and reinvented in the modern era by ideologues of all stripes and persuasions, including the Victorian upper classes and the Nazis.” The Victorians — or at least the Victorian aristocrats, like Pierre de Coubertin, who created the modern Olympics — wanted to believe that the ancient Olympics were a contest between wealthy aristocrats, amateurs who competed for the love of sport. Of course, the real ancient Olympics were win-at-all-costs competitions for prizes and glory, where athletes competed in the nude, with no signs of social rank.

Naturally, the Nazis, with their emphasis on physical fitness, invested a lot of national pride and money in the Berlin Olympics of 1936, and it’s the Nazis who are largely responsible for much of the pomp and circumstance we now associate with the games. In fact, the Nazis created the Olympic torch relay. From Olympic Flame:

For the ancient Greeks, fire had divine connotations — it was thought to have been stolen from the gods by Prometheus. Therefore, fire was also present at many of the sanctuaries in Olympia. A fire permanently burned on the altar of Hestia in Olympia. During the Olympic Games, which honoured Zeus, additional fires were lit at his temple and that of his wife, Hera. The modern Olympic flame is ignited at the site where the temple of Hera used to stand.

Fire did not appear at the modern Olympics until 1928. Dutch architect Jan Wils had included a tower in his design for the Olympic stadium for the 1928 Amsterdam Olympics and came up with the idea of having a fire burn throughout. On July 28, 1928 an employee of the Amsterdam electricity board lit the first Olympic fire in this so-called Marathontower, known as the “KLM’s ashtray” by the locals.

The idea of an Olympic Flame was met with enthusiasm, and was incorporated as a symbol of Olympism. German sports official and sports scientist Carl Diem conceived the idea of an Olympic torch relay for the 1936 Summer Olympics in Berlin. More than 3,000 runners carried the torch from Olympia to Berlin. German track and field athlete Fritz Schilgen was the last to carry the torch, igniting the flame in the stadium.

Protein Sports Drink May Boost Endurance

Thursday, July 22nd, 2004

Protein Sports Drink May Boost Endurance reports on a study that compared Accelerade, a sports drink with whey protein, to Gatorade, which contains no protein, just carbs:

Saunders and his colleagues tested the sports drinks by having trained cyclists pedal a stationary bike to the point of exhaustion while replenishing with either the protein-added or carb-only drink every 15 minutes. The athletes performed a second, more demanding ride the next day. One to two weeks later, they went through the process again, this time with the other drink.

Saunders’ team found that the men lasted 29 percent longer during the first test and 40 percent longer during the second test when they drank the protein-containing drink.

There were also signs of less exercise-induced muscle damage, according to the researchers. After the exercise tests, the cyclists’ blood levels of creatine phosphokinase — an enzyme released from muscles under stress — were lower when they consumed protein during the workout.

What’s Your Workout?

Tuesday, July 13th, 2004

This week, What’s Your Workout? looks at Sheri Woodruff, 38 years old, single, manager of financial communications for General Motors Corp. in New York City:

‘I don’t respond well to the idea of doing something because it’s good for me,’ she says. ‘For some, exercise is stress relief or quiet time for themselves, but for me it’s trying something new or challenging myself.’

Her membership at New York Sports Club across the street from her apartment is seldom used. She drops in about twice a month to use the treadmill or elliptical trainer but rarely lifts weights. She runs the three-mile reservoir loop in Central Park once or twice a week, but the majority of her weekly exercise comes from activities she’s signed up to do, such as her company softball league or bike-ride fund-raisers. She also plans her vacations around sporting activities. “My life is my workout,” Ms. Woodruff says.

Frankly, I wasn’t that interested in her workout routine, and she didn’t seem that impressive in pictures either. This bit caught my eye though:

Ms. Woodruff’s adventurous attitude toward fitness began as a teen. An athlete in high school, she played field hockey, lacrosse and was a catcher on the softball team. One day, the wrestling coach approached her in the weight room and asked if he could sponsor and train her as a power lifter. “I was 17 years old, and took it as a weird dare so I said ‘sure why not,’” she recalls. She went on to win the 127-pound-and-under division, squatting 400 pounds, in a high-school weight-lifting tournament.

OK, that’s impressive.

Steroids May Improve Tendon Repair After Surgery

Thursday, July 1st, 2004

For a long time, bodybuilders and other athletes have used anabolic steroids to recover quickly from injuries — in particular, “deca” (Deca Duraboline or nadrolone decanoate) has long had a reputation for fixing joint injuries. Steroids May Improve Tendon Repair After Surgery reports on a recent study demonstrating what athletes have known for a long time:

The researchers collected tendon samples from six people who were having rotator cuff surgery. Cells from these tendons were isolated and used to grow the bioengineered tendons.

Some of these tendons were treated with the anabolic steroid nandrolone decanoate, while others were not. Some tendons were also subjected to load testing, in which the tendons were stretched.

Tendons that had been treated with steroids and subjected to loading were stronger, denser and more elastic than other tendons, the researchers report in the American Journal of Sports Medicine. The steroid-treated tendons also had a more natural appearance than other tendons.

Naturally, “more testing needs to be done…”

The Way We Eat Now

Thursday, July 1st, 2004

The Way We Eat Now explains how human lifestyles — in terms of diet and exercise — have changed:

The old order Amish of Ontario, Canada, have escaped much of that advertising, and the TV viewing as well. They have an obesity rate of 4 percent, less than one-seventh the U.S. norm. Yet the Amish eat heartily, and not all health food: pancakes, ham, cake, and milk — but also ample amounts of fresh fruits and vegetables. It seems that the secret to the “Amish paradox” is their low-technology lifestyle, which entails vastly more physical activity than its modern correlate. David R. Bassett, a professor of exercise science at the University of Tennessee, gave pedometers to 98 of these Amish adults and found that the men averaged 18,000 steps per day, the women 14,000 — about nine miles and seven miles, respectively. The Amish men averaged 10 hours a week of vigorous activities like shoveling or tossing bales of hay (women, 3.5 hours) and 43 hours of moderate exertion like gardening or doing laundry (women, 39 hours).

“The Amish are not freaks,” says professor of anthropology Daniel Lieberman, a skeletal biologist. “They are just anachronisms. Human beings are adapted for endurance exercise. We evolved to be long-distance runners?running a marathon is not a freak activity. We can outrun just about any other creature.”

Though only a few pockets of hunter-gatherers remain on Earth, for the first couple of million years of our species’ evolution — 99.5 percent of the human experience — all people sustained themselves by hunting animals and gathering food from wild plants. Agriculture arose only 10,000 to 12,000 years ago, permitting more stable settlements and food supplies. Hunter-gatherers spend much of every day traveling: “Who ever heard of a sedentary hunter-gatherer?” asks Lieberman, laughing. (There were a few sedentary hunter-gatherers, he notes?in the Pacific Northwest where salmon ran plentifully.) But although humans are designed to be highly active, the chronic ailments of sedentary life and obesity, like diabetes and heart disease, typically turn fatal only when people are past reproductive age. Thus, natural selection doesn’t weed out couch potatoes.

Since the Industrial Revolution, and particularly in the last half-century, technology has enabled us to conduct an increasingly immobile daily life.

Humans, by the way, evolved to eat energy-dense foods like meat, nuts, and roots — which are difficult to eat without cooking (or other preparation):

Chimps’ jaws and teeth are bigger than ours, and they like to eat meat — they will work hard to get it — “but they can’t chew meat at all fast,” Wrangham says. “The rate at which they chew and swallow meat is equivalent to the way they eat fruits: 300 to 400 calories per hour.” In contrast, humans eating cooked, softened food of high caloric density can take in 2,000 calories during their daily hour of chewing and swallowing.

[...]

“The size of the human face has gotten about 12 percent smaller since the Paleolithic,” Lieberman says, “particularly around the oral cavity, due to the effects of mechanical loading on the size of the face. Fourteen thousand years ago, a much larger proportion of the face was between the bottom of the jaw and the nostrils.” The size of teeth has not decreased as fast (genetic factors control more of their variation); hence, modern teeth are actually too big for our mouths — wisdom teeth become impacted and require extraction.

What’s Your Workout?

Wednesday, June 30th, 2004

What’s Your Workout? is a new column looking “at the lifestyle and fitness routines of busy businesspeople” — starting with Jim Sud, executive vice president of growth and business development for Whole Foods Market Inc. in Austin, Texas:

Mr. Sud leaves his house at 6:30 a.m. and drives about 10 minutes to his health club, Mecca, located across the street from his office in downtown Austin. From there, he runs various loops around Town Lake, generally around 45-50 minutes. He ends up back at the gym, where he stretches and, twice a week, lifts weights. By 8:30 a.m., he’s at the office.

Some people are born to run. At 6:30 a.m. I’m not.

Television watching may hasten puberty

Tuesday, June 29th, 2004

According to Television watching may hasten puberty, watching television may reduce melatonin levels — and low melatonin levels hasten maturation:

Scientists at the University of Florence in Italy found that when youngsters were deprived of their TV sets, computers and video games, their melatonin production increased by an average 30 per cent.

?Girls are reaching puberty much earlier than in the 1950s. One reason is due to their average increase in weight; but another may be due to reduced levels of melatonin,? suggests Roberto Salti, who led the study. ?Animal studies have shown that low melatonin levels have an important role in promoting an early onset of puberty.?

(Hat tip to FuturePundit.)

Gene Doping

Thursday, June 24th, 2004

Gene Doping explains the brave new world of ergogenics:

Treatments that regenerate muscle, increase its strength, and protect it from degradation will soon be entering human clinical trials for muscle-wasting disorders. Among these are therapies that give patients a synthetic gene, which can last for years, producing high amounts of naturally occurring muscle-building chemicals. [...] The chemicals are indistinguishable from their natural counterparts and are only generated locally in the muscle tissue. Nothing enters the bloodstream, so officials will have nothing to detect in a blood or urine test.

Recently scientists matched up the harmless AAV virus with a synthetic gene that would produce IGF-I only in skeletal muscle:

After injecting this AAV-IGF-I combination into young mice, we saw that the muscles’ overall size and the rate at which they grew were 15 to 30 percent greater than normal, even though the mice were sedentary. Further, when we injected the gene into the muscles of middle-aged mice and then allowed them to reach old age, their muscles did not get any weaker.

To further evaluate this approach and its safety, Rosenthal created mice genetically engineered to overproduce IGF-I throughout their skeletal muscle. Encouragingly, they developed normally except for having skeletal muscles that ranged from 20 to 50 percent larger than those of regular mice. As these transgenic mice aged, their muscles retained a regenerative capacity typical of younger animals. Equally important, their IGF-I levels were elevated only in the muscles, not in the bloodstream, an important distinction because high circulating levels of IGF-I can cause cardiac problems and increase cancer risk. Subsequent experiments showed that IGF-I overproduction hastens muscle repair, even in mice with a severe form of muscular dystrophy.

This allowed them to “break the close connection between muscle use and its size” — but it certainly seems to work fine with weight training too:

We injected AAV-IGF-I into the muscle in just one leg of each of our lab rats and then subjected the animals to an eight-week weight-training protocol. At the end of the training, the AAV-IGF-I-injected muscles had gained nearly twice as much strength as the uninjected legs in the same animals. After training stopped, the injected muscles lost strength much more slowly than the unenhanced muscle. Even in sedentary rats, AAV-IGF-I provided a 15 percent strength increase, similar to what we saw in the earlier mouse experiments.

And that’s just IGF-1 he’s discussing, not myostatin inhibition.

Myostatin, Belgian Blue, and Flex Wheeler

Thursday, June 24th, 2004

The German toddler is supposedly the first human known to have the myostatin mutation (or, rather, to have two copies of it), but Double muscling in cattle due to mutations in the myostatin gene reports “that the myostatin gene is highly conserved among vertebrate species and that two breeds of cattle that are characterized by increased muscle mass (double muscling), Belgian Blue and Piedmontese, have mutations in the myostatin coding sequence.”

Muscle: The Myostatin Connection discusses the knock-out mice and at least one human case of the mutation:

The ultimate demonstration that myostatin regulates muscle size in humans is the work of a man named Victor Conte of BALCO laboratories. He has shown that champion bodybuilder Flex Wheeler actually possesses a mutation that has resulted in the deletion of his myostatin gene (much like that in Belgian Blue Cattle). This goes on to prove something else that has always been suspected…that champion bodybuilders possess some sort of genetic gift that allows them to become much more muscular than the average person. It seems that champion bodybuilders may owe much more to their genetics than they do to their training, supplement or drug use.

You may have heard of BALCO laboratories. Here’s their statement regarding Flex Wheeler:

Flex was a participant in a study we recently conducted in collaboration with the Department of Human Genetics at the University of Pittsburgh involving 62 men who made unusually large gains in muscle mass in response to strength training (extreme responders). Flex was one of only nine extreme responders that had the very rare “myostatin mutation.” Myostatin is the gene that “limits muscle growth.” Specifically, Flex had the rarest form of myostatin mutation at the “exon 2″ position on the gene. This simply means Flex has a much larger number of muscle fibers compared to the other subjects or the normal population. We believe that these are the very first myostatin mutation findings in humans and the results of this landmark study have already been submitted for publication. Flex was also found to have a very unusual type of the IGF-1 gene. In fact, Flex was the only participant in the study that did not have a “match.” All of the other extreme responders had at least three other subjects with a matching IGF-1 gene. Based upon Flex’s very unique genetic profile, we plan to expeditiously publish a scientific paper that reveals his complete genotype in specific detail. The publication of his remarkable genetic data should generate an enormous amount of media exposure.

(Addendum: Read more about Gene Doping and Fitness.)