The Four Thieves Vinegar Collective is a volunteer network of anarchists and hackers developing DIY medicines:
Four Thieves claims to have successfully synthesized five different kinds of pharmaceuticals, all of which were made using MicroLab. The device attempts to mimic an expensive machine usually only found in chemistry laboratories for a fraction of the price using readily available off-the-shelf parts. In the case of the MicroLab, the reaction chambers consist of a small mason jar mounted inside a larger mason jar with a 3D-printed lid whose printing instructions are available online. A few small plastic hoses and a thermistor to measure temperature are then attached through the lid to circulate fluids through the contraption to induce the chemical reactions necessary to manufacture various medicines. The whole process is automated using a small computer that costs about $30.
To date, Four Thieves has used the device to produce homemade Naloxone, a drug used to prevent opiate overdoses better known as Narcan; Daraprim, a drug that treats infections in people with HIV; Cabotegravir, a preventative HIV medicine that may only need to be taken four times per year; and mifepristone and misoprostol, two chemicals needed for pharmaceutical abortions.
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As for the DEA, none of the pharmaceuticals produced by the collective are controlled substance, so their possession is only subject to local laws about prescription medicines. If a person has a disease and prescription for the drug to treat that disease, they shouldn’t run into any legal issues if they were to manufacture their own medicine. Four Thieves is effectively just liberating information on how to manufacture certain medicines at home and developing the open source tools to make it happen. If someone decides to make drugs using the collective’s guides then that’s their own business, but Four Thieves doesn’t pretend that the information it releases is for “educational purposes only.”
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The catalyst for Four Thieves Vinegar Collective was a trip Laufer took to El Salvador in 2008 when he was still in graduate school. While visiting a rural medical clinic as part of an envoy documenting human rights violations in the country, he learned that it had run out of birth control three months prior. When the clinic contacted the central hospital in San Salvador, it was informed the other hospital had also run out of birth control. Laufer told me he was stunned that the hospitals were unable to source birth control, a relatively simple drug to manufacture that’s been around for over half-a-century. He figured if drug dealers in the country were able to use underground labs to manufacture illicit drugs, a similar approach could be taken to life-saving medicines.
This doesn’t seem wise:
Eric Von Hippel, an economist at MIT that researches “open innovation,” is enthusiastic about the promise of DIY drug production, but only under certain conditions. He cited a pilot program in the Netherlands that is exploring the independent production of medicines that are tailor made for individual patients as a good example of safe, DIY drug production. These drugs are made in the hospital by trained experts. Von Hippel believes it can be dangerous when patients undertake drug production on their own.
“If one does not do chemical reactions under just-right conditions, one can easily create dangerous by-products along with the drug one is trying to produce,” von Hippel told me in an email. “Careful control of reactor conditions is unlikely in DIY chemical reactors such as the MicroLab design offered for free by the Four Thieves Vinegar Collective.”His colleague, Harold DeMonaco, a visiting scientist at MIT, agreed. DeMonaco suggested that a more rational solution to the problems addressed would be for patients to work with compounding pharmacies. Compounding pharmacies prepare personalized medicine for their customers and DeMonaco said they are able to synthesize the same drugs Four Thieves is producing at low costs, but with “appropriate safeguards.”
“Unless the system is idiot proof and includes validation of the final product, the user is exposed to a laundry list of rather nasty stuff,” DeMonaco told me in an email. “Widespread use [of Four Thieves’ devices] would provide an entire new category for the Darwin Awards.”
I find their choice of drugs to produce…rather interesting.
Weren’t gay men with AIDS doing their own home-brew pharma at one point? Grasping at straws so to speak in an attempt to find the magic elixir to solve the problem for which conventional medicine has no remedy. Cocktails for medicine passed along in various journals and gay newspapers promising wonderful results which never occurred.
I don’t think mentioning the Darwin Awards is fair.
The Darwin Awards are a nasty habit of sneering and gloating when reckless people get themselves killed by an obvious lack of common-sense caution.
These emergency drugs are intended for desperately poor patients who will die if they don’t get medicine. The patients are not being reckless: they are just poor. They are trying to minimize their risk of death: they do not lack caution.
If you are starving to death, and you try to survive by eating food that has a small chance of being poisonous, you’re doing your best in a difficult situation. Getting a Darwin Award for dying just proves that the people who hand out such mockery are psychologically maladjusted.