Cane Toads are poisonous:
All stages of the Cane Toad’s life-cycle are poisonous. The venom produced by the parotoid glands acts principally on the heart. No humans have died in Australia from Cane Toad poison but overseas, people have died after eating toads and even soup made from boiled toad eggs. Cane Toads are also poisonous to pets and in Hawaii up to 50 dogs a year have died after mouthing Cane Toads. Signs of poisoning through ingestion include profuse salivation, twitching, vomiting, shallow breathing, and collapse of the hind limbs. Death may occur by cardiac arrest within 15 minutes.Australian native fauna that have been killed by eating or mouthing Cane Toads include goannas, Freshwater Crocodile, Tiger Snake, Red-bellied Black Snake, Death Adder, Dingo and Western Quoll.
A Cane Toad responds to threat by turning side-on so its parotoid glands are directed towards the attacker. The venom usually oozes out of the glands, but toads can squirt a fine spray for a short distance if they are handled roughly. The venom is absorbed through mucous membranes such as eyes, mouth and nose, and in humans may cause intense pain, temporary blindness and inflammation.