I have some personal experience here. About 70 of them.

These drugs are very safe… usually. I’m talking about LSD, mescaline and mushrooms – not about peyote, MDMA (ecstasy, molly), PCP, or ketamine.
Mushrooms are hit or miss.

All 3 of the drugs are very powerful levers on the mind unsuited to therapeutic use. From a clinical perspective their effects are profound, but random. And if you slip me into a usual doctors office, that would be a big no thank you right off the bat.

The good thing about these drugs is their nonexistent abuse potential. You can only take them once a month, although my experience was more like 6 to 8 weeks. And like steroids, you have a lifetime dosage limit. Somewhere between 50 and 100 doses it stops working.

Medically, I could see very small doses useful for narcolepsy and related disorders. Say 5 micrograms, where a typical street dose is 70 to 100, and most take 2 or 3 doses. Smoking cessation… Ha!

As palliative care in a hospice setting – no way. My bullshit klaxon just rang a 10 on that one. Wrong in so many ways.