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	<title>Comments on: Trust, But Verify</title>
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	<description>From the ancient Greek for equality in freedom of speech; an eclectic mix of thoughts, large and small</description>
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		<title>By: Scipio Americanus</title>
		<link>https://www.isegoria.net/2013/11/trust-but-verify/comment-page-1/#comment-1020929</link>
		<dc:creator>Scipio Americanus</dc:creator>
		<pubDate>Thu, 14 Nov 2013 14:15:55 +0000</pubDate>
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		<description><![CDATA[That probably wouldn&#039;t hurt, but the issues with the conduct of modern science are a lot deeper than that. The article points out that the field has grown enormously in the last century, but what it somewhat misses is the change in the character of Science as a profession. It has gone from a self-selected calling to a job you train for and has lost a lot from that transition. 

It worked out for a while as society converted more of its potential scientists into actual ones, but there are only so many such people and now I would judge we are well past the point of diminishing returns. Thus the precipitous drop in the quality of research and the proportional increase in the amount of trivial work being done. Unfortunately, it seems from my experience that this cultural change seems to disincentivise the &quot;true&quot; scientists who are perhaps less than brilliant at navigating complex grant bureaucracies and academic politics.]]></description>
		<content:encoded><![CDATA[<p>That probably wouldn&#8217;t hurt, but the issues with the conduct of modern science are a lot deeper than that. The article points out that the field has grown enormously in the last century, but what it somewhat misses is the change in the character of Science as a profession. It has gone from a self-selected calling to a job you train for and has lost a lot from that transition. </p>
<p>It worked out for a while as society converted more of its potential scientists into actual ones, but there are only so many such people and now I would judge we are well past the point of diminishing returns. Thus the precipitous drop in the quality of research and the proportional increase in the amount of trivial work being done. Unfortunately, it seems from my experience that this cultural change seems to disincentivise the &#8220;true&#8221; scientists who are perhaps less than brilliant at navigating complex grant bureaucracies and academic politics.</p>
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		<title>By: Ross</title>
		<link>https://www.isegoria.net/2013/11/trust-but-verify/comment-page-1/#comment-1020487</link>
		<dc:creator>Ross</dc:creator>
		<pubDate>Thu, 14 Nov 2013 03:11:41 +0000</pubDate>
		<guid isPermaLink="false">http://www.isegoria.net/?p=33419#comment-1020487</guid>
		<description><![CDATA[Ah, false positives and irreproducible results! I dub thee: The Ioannidis Valley of Death. (After John &quot;Most Published Results are False&quot; Ioannidis). 

New results now indicate reproducibility would be significantly boosted (ha ha, little pun there) and false positives similarly suppressed by raising the bar for &quot;p&quot; to .005 and .001 for significant and highly significant results, respectively. 

http://www.pnas.org/content/early/2013/10/28/1313476110.full.pdf

Certainly this comes at the cost of more expensive and slower science (need more samples, you see), but maybe a more solid footing will bear out the truth in &quot;slow is smooth; smooth is fast&quot;.]]></description>
		<content:encoded><![CDATA[<p>Ah, false positives and irreproducible results! I dub thee: The Ioannidis Valley of Death. (After John &#8220;Most Published Results are False&#8221; Ioannidis). </p>
<p>New results now indicate reproducibility would be significantly boosted (ha ha, little pun there) and false positives similarly suppressed by raising the bar for &#8220;p&#8221; to .005 and .001 for significant and highly significant results, respectively. </p>
<p><a href="http://www.pnas.org/content/early/2013/10/28/1313476110.full.pdf" >http://www.pnas.org/content/early/2013/10/28/1313476110.full.pdf</a></p>
<p>Certainly this comes at the cost of more expensive and slower science (need more samples, you see), but maybe a more solid footing will bear out the truth in &#8220;slow is smooth; smooth is fast&#8221;.</p>
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